Ernest Jones, which was located in the Petergate Mall in The Broadway, is now shut.
The jeweller, established in 1949, has specialised in diamonds and watches for more than 50 years.
Its stores stock including Breitling SA, Omega SA, TAG Heuer, Cartier SA, Gucci, and Emporio Armani.
A sign on the shop window in The Broadway said: “This store has now closed.
“In the meantime, we’d be delighted to help celebrate your story at your nearest store (Commercial Street, Leeds) or at www.ernestjones.co.uk
“If you have an order, repair or deposit with us we’ll be in touch.”
It comes after jeweller H. Samuel reopened after undergoing a makeover for a month.